Xceptional Instruments

Three-Tec AG

Hybrid Micro Compounder

One frame, three barrel sizes — interchangeable 5, 9, and 12 mm twin-screw barrels, tool-free in minutes.

cGMP21 CFR Part 11FDA316L
Three-Tec Hybrid Micro Compounder showing the single-frame chassis with interchangeable 5, 9, and 12 mm twin-screw barrels

01 / 04OVERVIEW

The Hybrid Micro Compounder mounts interchangeable 5, 9, and 12 mm co-rotating twin-screw barrels on a single chassis. Switch between gram-scale screening and pre-production throughput without changing extruders — barrel changeover is tool-free and takes under five minutes. The frame accommodates the full torque range from 2.5 Nm (5 mm) through 20 Nm (12 mm) with a unified Siemens S7-1500 control platform. An optional recirculation channel extends residence time for demanding formulations that require longer mixing or reaction. All contact surfaces are 316L stainless.

02 / 04FEATURES

Three barrel sizes on one frame — 5 mm, 9 mm, and 12 mm
Tool-free barrel changeover in under five minutes
Optional recirculation channel for extended residence time
Unified Siemens S7-1500 control across all barrel sizes
Covers gram-scale screening through pre-production throughput
316L stainless contact surfaces, cGMP-ready
Modular L/D 15:1 to 40:1 per barrel size

03 / 04SPECIFICATIONS

Technical data

GEOMETRY
Barrel sizes5 mm / 9 mm / 12 mm (interchangeable)
L/D ratio15:1 – 40:1 per barrel
Changeover time< 5 minutes, tool-free
Recirculation channelOptional
DRIVE
Max torque (5 mm)2.5 Nm
Max torque (9 mm)14.5 Nm
Max torque (12 mm)20 Nm
Screw speed1–1,000 rpm
THERMAL
Max temperature230 °C (400 °C optional)
Heating zonesUp to 12 independent zones
CONTROL
PLCSiemens S7-1500
HMISiemens 12" touchscreen
Data loggingIntegrated, CSV export
COMPLIANCE
Contact material316L stainless (Ra 0.8 µm)
StandardscGMP, FDA, 21 CFR Part 11 optional
Hybrid Micro Compounder system overview with Siemens PLC control station and barrel assembly
Fig. 02Hybrid Micro Compounder system overview with Siemens PLC control station and barrel assembly

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